Spider venom could cure erectile dysfunction – Brazilian scientists

Author: Chany Ninrew | Published: Monday, October 2, 2023

Banana spider in a container. (DOUGLAS MAGNO/AFP or licensors).

Researchers in Brazil are investigating whether a banana spider venom could help treat erectile dysfunction after people bitten by the insect are observed to suffer a prolonged and painful erection, according to French news agency AFP.

It was three decades ago when researchers began studying a curious side effect of banana spider bites after the toxin left victims with a painful and persistent erection.

AFP reports scientists were inspired to develop a synthetic molecule using some properties of the spider’s poison to create a gel to treat erectile dysfunction.

The banana spider’s bite is known to cause painful, prolonged erections and scientists are now using its venom to develop a synthetic molecule.

According to EuroNews, Marcia Helena Borges, researcher at FUNED (Ezequiel Dias Foundation) said they “saw that patients who came to the clinic and had been bitten by this spider presented a characteristic symptom, which was priapism, which is a painful and prolonged erection.”

The molecule triggers the release of nitric oxide, a chemical essential for erections as it increases blood circulation and allows blood vessels to widen.

Covered in thick brown hair, and with a maximum size of up to 15 centimeters, this arachnid is one of the most venomous in the world.

Maria Elena, professor at UFMG (Federal University of Minas Gerais) told AFP the research could be especially important for men who have had their prostate removed.

“There is great resistance among men to undergo radical prostate surgery, for example in the case of cancer, because this leads to erectile dysfunction,” she said.

“And in this case, as the peptides are active in men who have had their prostate removed, it can further enable early cancer treatment.”

Erectile dysfunction affects tens of millions of men around the world.

Biologist Carolina Nunes says that the compound created by the researchers has “great potential to become an internationally recognized medicine.”

After the first phase of clinical trials was approved by Brazil’s Anvisa regulatory agency, the medication has now moved into the second of three phases before being approved for sale.

Maria Elena de Lima, a UFMG researcher said the discovery of a potential erectile dysfunction treatment was a message “not to destroy animals, even poisonous ones, because there is a real library of molecules that are still unknown.”

Additional information in this story were obtained from Euronews and Agence France Presse.

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